<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"><channel><title>EricH</title><description>ReframeIt.com comments by EricH</description><link>http://reframeit.com/users/5Wqm1IrCBEl/comments</link><item><title>Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor @ http://www.iii.co.uk" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.iii.co.uk"&gt;Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;This seems to be an overall trend. We will see how low things will go.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;CFD Trading and Spread Betting margins cut</description><pubDate>Tue, 27 Oct 2009 18:02:38 +0000</pubDate><author>EricH</author><comment>This seems to be an overall trend. We will see how low things will go.
</comment><reference_text>CFD Trading and Spread Betting margins cut</reference_text><link>http://reframeit.com/comments/625LZs44ni3</link><guid isPermaLink="true">http://reframeit.com/comments/625LZs44ni3</guid></item><item><title>Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor @ http://www.iii.co.uk" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.iii.co.uk"&gt;Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;This is an interesting site. Significant content and well put-together.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;http://www.iii.co.uk/i/logos/uk_logo2.gif</description><pubDate>Tue, 27 Oct 2009 17:58:21 +0000</pubDate><author>EricH</author><comment>This is an interesting site. Significant content and well put-together.
</comment><reference_text>http://www.iii.co.uk/i/logos/uk_logo2.gif</reference_text><link>http://reframeit.com/comments/D0jxrFo_dA</link><guid isPermaLink="true">http://reframeit.com/comments/D0jxrFo_dA</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;I have some ideas on this. Call me later.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;So far, most of the PEG conjugates comprise of a protein, which in the native form has serious shortcomings that limit the full exploitation of its therapeutic action</description><pubDate>Thu, 20 Aug 2009 20:19:24 +0000</pubDate><author>EricH</author><comment>I have some ideas on this. Call me later.
</comment><reference_text>So far, most of the PEG conjugates comprise of a protein, which in the native form has serious shortcomings that limit the full exploitation of its therapeutic action</reference_text><link>http://reframeit.com/comments/BombWGDHRUt</link><guid isPermaLink="true">http://reframeit.com/comments/BombWGDHRUt</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;You can also contact them via email at Department of Pharmaceutical Sciences, University of Padua, Italy. email: Andrea Cavaggioni (andrea.cavaggioni@unipd.it) ... Universit&#224; di Padova, Via Marzolo 3, 35100 Padova, Italia&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</description><pubDate>Thu, 20 Aug 2009 20:15:31 +0000</pubDate><author>EricH</author><comment>You can also contact them via email at Department of Pharmaceutical Sciences, University of Padua, Italy. email: Andrea Cavaggioni (andrea.cavaggioni@unipd.it) ... Universit&#224; di Padova, Via Marzolo 3, 35100 Padova, Italia</comment><reference_text>Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</reference_text><link>http://reframeit.com/comments/6pYycj5ycqR</link><guid isPermaLink="true">http://reframeit.com/comments/6pYycj5ycqR</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;Would also like to add,  It produces alterations in the physiochemical properties.&#160; For more see http://en.wikipedia.org/wiki/PEGylation
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;PEGylation</description><pubDate>Thu, 20 Aug 2009 20:10:12 +0000</pubDate><author>EricH</author><comment>Would also like to add,  It produces alterations in the physiochemical properties.&#160; For more see http://en.wikipedia.org/wiki/PEGylation
</comment><reference_text>PEGylation</reference_text><link>http://reframeit.com/comments/4qPo_JSSEpB</link><guid isPermaLink="true">http://reframeit.com/comments/4qPo_JSSEpB</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;The covalent attachment of PEG to a drug or therapeutic protein can "mask" the agent from the host's immune system (reduced immunogenicity.&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;PEGylation</description><pubDate>Thu, 20 Aug 2009 20:07:31 +0000</pubDate><author>EricH</author><comment>The covalent attachment of PEG to a drug or therapeutic protein can "mask" the agent from the host's immune system (reduced immunogenicity.</comment><reference_text>PEGylation</reference_text><link>http://reframeit.com/comments/F88ODP6BP-8</link><guid isPermaLink="true">http://reframeit.com/comments/F88ODP6BP-8</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;These folks do some excellent research.&#160; Check out this example: http://lib.bioinfo.pl/auid:2414641.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</description><pubDate>Thu, 20 Aug 2009 20:04:24 +0000</pubDate><author>EricH</author><comment>These folks do some excellent research.&#160; Check out this example: http://lib.bioinfo.pl/auid:2414641.
</comment><reference_text>Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</reference_text><link>http://reframeit.com/comments/9bg-7At-Vxw</link><guid isPermaLink="true">http://reframeit.com/comments/9bg-7At-Vxw</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;This journal has a reasonably broad scope.&#160; Check it out here: http://www.elsevier.com/wps/find/journaldescription.cws_home/505508/description#description

&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Advanced Drug Delivery Reviews theme</description><pubDate>Thu, 20 Aug 2009 19:51:29 +0000</pubDate><author>EricH</author><comment>This journal has a reasonably broad scope.&#160; Check it out here: http://www.elsevier.com/wps/find/journaldescription.cws_home/505508/description#description

</comment><reference_text>Advanced Drug Delivery Reviews theme</reference_text><link>http://reframeit.com/comments/Df4W-so7EDi</link><guid isPermaLink="true">http://reframeit.com/comments/Df4W-so7EDi</guid></item><item><title>California Rejects Michigan Offer to House Prisoners - WSJ.com</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="California Rejects Michigan Offer to House Prisoners - WSJ.com @ http://online.wsj.com/article/SB125061475758840467.html" href="http://reframeit.com/pages?uri=http%253A%252F%252Fonline.wsj.com%252Farticle%252FSB125061475758840467.html"&gt;California Rejects Michigan Offer to House Prisoners - WSJ.com&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;Inadequate medical resources? Coming from California that does not sound credible...
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;inadequate medical resources</description><pubDate>Tue, 18 Aug 2009 23:24:45 +0000</pubDate><author>EricH</author><comment>Inadequate medical resources? Coming from California that does not sound credible...
</comment><reference_text>inadequate medical resources</reference_text><link>http://reframeit.com/comments/4X2KFeumr6u</link><guid isPermaLink="true">http://reframeit.com/comments/4X2KFeumr6u</guid></item><item><title>Damascus Agrees to Help Monitor Iraqi Border - WSJ.com</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="Damascus Agrees to Help Monitor Iraqi Border - WSJ.com @ http://online.wsj.com/article/SB125063522892541469.html" href="http://reframeit.com/pages?uri=http%253A%252F%252Fonline.wsj.com%252Farticle%252FSB125063522892541469.html"&gt;Damascus Agrees to Help Monitor Iraqi Border - WSJ.com&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;Not sure I would have brought Syria in to be a partner here.&#160; Perhaps similar with doing a deal with the Cali cartel to monitor customs...
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Damascus Agrees to Help Monitor Iraqi Border</description><pubDate>Tue, 18 Aug 2009 23:20:35 +0000</pubDate><author>EricH</author><comment>Not sure I would have brought Syria in to be a partner here.&#160; Perhaps similar with doing a deal with the Cali cartel to monitor customs...
</comment><reference_text>Damascus Agrees to Help Monitor Iraqi Border</reference_text><link>http://reframeit.com/comments/Fli3NVBUCuI</link><guid isPermaLink="true">http://reframeit.com/comments/Fli3NVBUCuI</guid></item></channel></rss><?xml version="1.0" encoding="UTF-8"?><rss version="2.0"><channel><title>EricH</title><description>ReframeIt.com comments by EricH</description><link>http://reframeit.com/users/5Wqm1IrCBEl/comments</link><item><title>Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor @ http://www.iii.co.uk" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.iii.co.uk"&gt;Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;This seems to be an overall trend. We will see how low things will go.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;CFD Trading and Spread Betting margins cut</description><pubDate>Tue, 27 Oct 2009 18:02:38 +0000</pubDate><author>EricH</author><comment>This seems to be an overall trend. We will see how low things will go.
</comment><reference_text>CFD Trading and Spread Betting margins cut</reference_text><link>http://reframeit.com/comments/625LZs44ni3</link><guid isPermaLink="true">http://reframeit.com/comments/625LZs44ni3</guid></item><item><title>Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor @ http://www.iii.co.uk" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.iii.co.uk"&gt;Free Portfolio, Share dealing, ISAs, PEPs, SIPPs, CFDs, Spread betting - Interactive Investor&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;This is an interesting site. Significant content and well put-together.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;http://www.iii.co.uk/i/logos/uk_logo2.gif</description><pubDate>Tue, 27 Oct 2009 17:58:21 +0000</pubDate><author>EricH</author><comment>This is an interesting site. Significant content and well put-together.
</comment><reference_text>http://www.iii.co.uk/i/logos/uk_logo2.gif</reference_text><link>http://reframeit.com/comments/D0jxrFo_dA</link><guid isPermaLink="true">http://reframeit.com/comments/D0jxrFo_dA</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;I have some ideas on this. Call me later.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;So far, most of the PEG conjugates comprise of a protein, which in the native form has serious shortcomings that limit the full exploitation of its therapeutic action</description><pubDate>Thu, 20 Aug 2009 20:19:24 +0000</pubDate><author>EricH</author><comment>I have some ideas on this. Call me later.
</comment><reference_text>So far, most of the PEG conjugates comprise of a protein, which in the native form has serious shortcomings that limit the full exploitation of its therapeutic action</reference_text><link>http://reframeit.com/comments/BombWGDHRUt</link><guid isPermaLink="true">http://reframeit.com/comments/BombWGDHRUt</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;You can also contact them via email at Department of Pharmaceutical Sciences, University of Padua, Italy. email: Andrea Cavaggioni (andrea.cavaggioni@unipd.it) ... Universit&#224; di Padova, Via Marzolo 3, 35100 Padova, Italia&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</description><pubDate>Thu, 20 Aug 2009 20:15:31 +0000</pubDate><author>EricH</author><comment>You can also contact them via email at Department of Pharmaceutical Sciences, University of Padua, Italy. email: Andrea Cavaggioni (andrea.cavaggioni@unipd.it) ... Universit&#224; di Padova, Via Marzolo 3, 35100 Padova, Italia</comment><reference_text>Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</reference_text><link>http://reframeit.com/comments/6pYycj5ycqR</link><guid isPermaLink="true">http://reframeit.com/comments/6pYycj5ycqR</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;Would also like to add,  It produces alterations in the physiochemical properties.&#160; For more see http://en.wikipedia.org/wiki/PEGylation
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;PEGylation</description><pubDate>Thu, 20 Aug 2009 20:10:12 +0000</pubDate><author>EricH</author><comment>Would also like to add,  It produces alterations in the physiochemical properties.&#160; For more see http://en.wikipedia.org/wiki/PEGylation
</comment><reference_text>PEGylation</reference_text><link>http://reframeit.com/comments/4qPo_JSSEpB</link><guid isPermaLink="true">http://reframeit.com/comments/4qPo_JSSEpB</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;The covalent attachment of PEG to a drug or therapeutic protein can "mask" the agent from the host's immune system (reduced immunogenicity.&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;PEGylation</description><pubDate>Thu, 20 Aug 2009 20:07:31 +0000</pubDate><author>EricH</author><comment>The covalent attachment of PEG to a drug or therapeutic protein can "mask" the agent from the host's immune system (reduced immunogenicity.</comment><reference_text>PEGylation</reference_text><link>http://reframeit.com/comments/F88ODP6BP-8</link><guid isPermaLink="true">http://reframeit.com/comments/F88ODP6BP-8</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;These folks do some excellent research.&#160; Check out this example: http://lib.bioinfo.pl/auid:2414641.
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</description><pubDate>Thu, 20 Aug 2009 20:04:24 +0000</pubDate><author>EricH</author><comment>These folks do some excellent research.&#160; Check out this example: http://lib.bioinfo.pl/auid:2414641.
</comment><reference_text>Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35100 Padova, Italy</reference_text><link>http://reframeit.com/comments/9bg-7At-Vxw</link><guid isPermaLink="true">http://reframeit.com/comments/9bg-7At-Vxw</guid></item><item><title>ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview @ http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T3R-4WYJSK6-2&amp;_user=10&amp;_rdoc=1&amp;_fmt=&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=77d9ccfe95de2c72535ea6a77588c5b6" href="http://reframeit.com/pages?uri=http%253A%252F%252Fwww.sciencedirect.com%252Fscience%253F_ob%253DArticleURL%2526_udi%253DB6T3R-4WYJSK6-2%2526_user%253D10%2526_rdoc%253D1%2526_fmt%253D%2526_orig%253Dsearch%2526_sort%253Dd%2526_docanchor%253D%2526view%253Dc%2526_acct%253DC000050221%2526_version%253D1%2526_urlVersion%253D0%2526_userid%253D10%2526md5%253D77d9ccfe95de2c72535ea6a77588c5b6"&gt;ScienceDirect - Advanced Drug Delivery Reviews : PEG conjugates in clinical development or use as anticancer agents: An overview&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;This journal has a reasonably broad scope.&#160; Check it out here: http://www.elsevier.com/wps/find/journaldescription.cws_home/505508/description#description

&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Advanced Drug Delivery Reviews theme</description><pubDate>Thu, 20 Aug 2009 19:51:29 +0000</pubDate><author>EricH</author><comment>This journal has a reasonably broad scope.&#160; Check it out here: http://www.elsevier.com/wps/find/journaldescription.cws_home/505508/description#description

</comment><reference_text>Advanced Drug Delivery Reviews theme</reference_text><link>http://reframeit.com/comments/Df4W-so7EDi</link><guid isPermaLink="true">http://reframeit.com/comments/Df4W-so7EDi</guid></item><item><title>California Rejects Michigan Offer to House Prisoners - WSJ.com</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="California Rejects Michigan Offer to House Prisoners - WSJ.com @ http://online.wsj.com/article/SB125061475758840467.html" href="http://reframeit.com/pages?uri=http%253A%252F%252Fonline.wsj.com%252Farticle%252FSB125061475758840467.html"&gt;California Rejects Michigan Offer to House Prisoners - WSJ.com&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;Inadequate medical resources? Coming from California that does not sound credible...
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;inadequate medical resources</description><pubDate>Tue, 18 Aug 2009 23:24:45 +0000</pubDate><author>EricH</author><comment>Inadequate medical resources? Coming from California that does not sound credible...
</comment><reference_text>inadequate medical resources</reference_text><link>http://reframeit.com/comments/4X2KFeumr6u</link><guid isPermaLink="true">http://reframeit.com/comments/4X2KFeumr6u</guid></item><item><title>Damascus Agrees to Help Monitor Iraqi Border - WSJ.com</title><description>EricH made a new comment on:&lt;br/&gt;&lt;br/&gt;&lt;a class="" rel="" title="Damascus Agrees to Help Monitor Iraqi Border - WSJ.com @ http://online.wsj.com/article/SB125063522892541469.html" href="http://reframeit.com/pages?uri=http%253A%252F%252Fonline.wsj.com%252Farticle%252FSB125063522892541469.html"&gt;Damascus Agrees to Help Monitor Iraqi Border - WSJ.com&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;EricH's comment is:&lt;br/&gt;&lt;br/&gt;Not sure I would have brought Syria in to be a partner here.&#160; Perhaps similar with doing a deal with the Cali cartel to monitor customs...
&lt;br/&gt;&lt;br/&gt;This comment references the following:&lt;br/&gt;&lt;br/&gt;Damascus Agrees to Help Monitor Iraqi Border</description><pubDate>Tue, 18 Aug 2009 23:20:35 +0000</pubDate><author>EricH</author><comment>Not sure I would have brought Syria in to be a partner here.&#160; Perhaps similar with doing a deal with the Cali cartel to monitor customs...
</comment><reference_text>Damascus Agrees to Help Monitor Iraqi Border</reference_text><link>http://reframeit.com/comments/Fli3NVBUCuI</link><guid isPermaLink="true">http://reframeit.com/comments/Fli3NVBUCuI</guid></item></channel></rss>